Here's the first look at an emotional scene from the upcoming Anna Nicole Smith biopic ... and it's dramatic.

Abbie Cornish plays Anna Nicole in "Trust Me, I'm a Doctor" ... and in the clip, obtained by TMZ, she's crying in a hospital bed and telling her doctor she feels like she can't help but "f*** things up."

Kal Penn plays Anna Nicole's doctor, Dr. Sandeep Kapoor, as she emotionally exclaims that having her son, Daniel, was the best thing she's ever done, expressing how she wants to bring something good into the world. The film is set for release on October 16.

As you know, Daniel tragically died in 2006, just after her daughter Dannielynn was born.

Larry Birkhead -- Dannielynn's father -- is pissed about the new movie ... saying Dr. Kapoor has been milking her death for the past 2 decades.

The new film tells Kapoor's story ... he faced felony charges for prescribing her medication before her death, but was ultimately acquitted and cleared of any wrongdoing.